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Cellosaurus SHEPrETO100 (CVCL_RR79)

[Text version]
Cell line name SHEPrETO100
Accession CVCL_RR79
Resource Identification Initiative To cite this cell line use: SHEPrETO100 (RRID:CVCL_RR79)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:4911; Etoposide (VP-16).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; 427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0524 (SH-EP)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
Web pages https://www.wass-michaelislab.org/rccl.php
Publications

PubMed=24466371; DOI=10.1593/tlo.13544
Loschmann N., Michaelis M., Rothweiler F., Zehner R., Cinatl J., Voges Y., Sharifi M., Riecken K., Meyer J., von Deimling A., Fichtner I., Ghafourian T., Westermann F., Cinatl J. Jr.
Testing of SNS-032 in a panel of human neuroblastoma cell lines with acquired resistance to a broad range of drugs.
Transl. Oncol. 6:685-696(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RR79
Encyclopedic resources Wikidata; Q54953307
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number10