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Cellosaurus UKF-NB-3rNutlin10muM (CVCL_RS05)

[Text version]
Cell line name UKF-NB-3rNutlin10muM
Accession CVCL_RS05
Resource Identification Initiative To cite this cell line use: UKF-NB-3rNutlin10muM (RRID:CVCL_RS05)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Selected for resistance to: ChEBI; CHEBI:46742; Nutlin-3.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9904 (UKF-NB-3)
Sex of cell Female
Category Cancer cell line
Web pages https://www.wass-michaelislab.org/rccl.php
Publications

PubMed=22170099; DOI=10.1038/cddis.2011.129
Michaelis M., Rothweiler F., Barth S., Cinatl J., van Rikxoort M., Loschmann N., Voges Y., Breitling R., von Deimling A., Rodel F., Weber K., Fehse B., Mack E., Stiewe T., Doerr H.-W., Speidel D., Cinatl J. Jr.
Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells.
Cell Death Dis. 2:e243.1-e243.8(2011)

PubMed=24466371; DOI=10.1593/tlo.13544
Loschmann N., Michaelis M., Rothweiler F., Zehner R., Cinatl J., Voges Y., Sharifi M., Riecken K., Meyer J., von Deimling A., Fichtner I., Ghafourian T., Westermann F., Cinatl J. Jr.
Testing of SNS-032 in a panel of human neuroblastoma cell lines with acquired resistance to a broad range of drugs.
Transl. Oncol. 6:685-696(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RS05
Encyclopedic resources Wikidata; Q54990350
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number10