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Cellosaurus T24rYM155_20nM (CVCL_RS42)

[Text version]

Cell line name T24rYM155_20nM
Synonyms T24rYM155(20nM)
Accession CVCL_RS42
Resource Identification Initiative To cite this cell line use: T24rYM155_20nM (RRID:CVCL_RS42)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian; Swedish.
Selected for resistance to: ChEBI; CHEBI:139608; Sepantronium bromide (YM155).
Derived from sampling site: Urinary bladder.
Sequence variations Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0554 (T24)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Web pages http://www.wass-michaelislab.org/rccl.php
Cross-references
Other Wikidata; Q54971467
Entry history
Entry creation05-Mar-2018
Last entry update20-May-2021
Version number8