Cellosaurus H82R (CVCL_RS66)

Cell line name H82R
Accession CVCL_RS66
Resource Identification Initiative To cite this cell line use: H82R (RRID:CVCL_RS66)
Comments Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Sequence variation: TP53 c.375G>T; impairs TP53 splicing dramatically (from parent cell line).
Disease Small cell lung carcinoma (NCIt: C4917)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1591 (NCI-H82)
Sex of cell Male
Age at sampling 41Y
Category Cancer cell line

PubMed=27610620; DOI=10.1371/journal.pone.0162925
Yan F., Pang J., Peng Y., Molina J.R., Yang P., Liu S.
Elevated cellular PD1/PD-L1 expression confers acquired resistance to cisplatin in small cell lung cancer cells.
PLoS ONE 11:E0162925-E0162925(2016)