| Cell line name | Hi-5 Rix4446 |
|---|---|
| Synonyms | Hi-5 Rix 4446; Rix4446 |
| Accession | CVCL_RW20 |
| Resource Identification Initiative | To cite this cell line use: Hi-5 Rix4446 (RRID:CVCL_RW20) |
| Comments | Group: Insect cell line. Group: Recombinant protein production insect cell line. Group: Vaccine production cell line. Biotechnology: Used for the production of the papilloma vaccine Cervarix. The C-terminally truncated proteins L1 of HPV-16 and HPV-18 are separately produced in this cell line using a recombinant baculovirus expression system. |
| Species of origin | Trichoplusia ni (Cabbage looper)
(NCBI Taxonomy: 7111)
|
| Hierarchy | Parent: CVCL_C190 (BTI-Tn-5B1-4) |
| Sex of cell | Sex unspecified |
| Age at sampling | Embryonic stage |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=22265860; DOI=10.1016/j.vaccine.2012.01.016 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54889518 |
| Entry history | |
| Entry creation | 05-Mar-2018 |
| Last entry update | 20-May-2021 |
| Version number | 5 |