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Cellosaurus OR6 [Chlorocebus aethiops] (CVCL_RW40)

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Cell line name OR6 [Chlorocebus aethiops]
Synonyms ouaR6
Accession CVCL_RW40
Resource Identification Initiative To cite this cell line use: OR6 [Chlorocebus aethiops] (RRID:CVCL_RW40)
Comments Group: Non-human primate cell line.
Selected for resistance to: ChEBI; CHEBI:472805; Ouabain.
Transfected with: HGNC; 799; ATP1A1.
Transfected with: MGI; MGI:88105; Atp1a1 (with p.Ile798Thr).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from sampling site: Kidney.
Species of origin Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) (NCBI Taxonomy: 9534)
Hierarchy Parent: CVCL_0229 (CV-1)
Sex of cell Male
Age at sampling Adult
Category Transformed cell line

PubMed=6324196; DOI=10.1073/pnas.81.5.1489
Levenson R., Racaniello V., Albritton L., Housman D.E.
Molecular cloning of the mouse ouabain-resistance gene.
Proc. Natl. Acad. Sci. U.S.A. 81:1489-1493(1984)

PubMed=2981832; DOI=10.1016/S0021-9258(20)71215-9
English L.H., Epstein J., Cantley L.T., Housman D.E., Levenson R.
Expression of an ouabain resistance gene in transfected cells Ouabain treatment induces a K+-transport system.
J. Biol. Chem. 260:1114-1119(1985)

PubMed=2826456; DOI=10.1016/S0021-9258(19)35398-0
Schulz J.T., Cantley L.C.
CV-1 cell recipients of the mouse ouabain resistance gene express a ouabain-insensitive Na,K-ATPase after growth in cardioactive steroids.
J. Biol. Chem. 263:624-632(1988)

PubMed=8195174; DOI=10.1016/S0021-9258(17)36614-0
Cantley L.G., Cunha M.J., Zhou X.-M.
Ouabain-resistant OR6 cells express the murine alpha 1-subunit of the Na,K-ATPase with a T797-I797 substitution.
J. Biol. Chem. 269:15358-15361(1994)

Other Wikidata; Q54936488
Entry history
Entry creation05-Mar-2018
Last entry update12-Mar-2020
Version number3