| Cell line name |
V79 SP5 |
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| Synonyms |
V79 Sp5; V79/SP5; SP5; Sp5; SP5/V79 |
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| Accession |
CVCL_RW41 |
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| Resource Identification Initiative |
To cite this cell line use: V79 SP5 (RRID:CVCL_RW41) |
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| Comments |
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553. |
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| Sequence variations |
- Mutation; UniProtKB; P00494; Hprt1; Unexplicit; Ex2dup; Zygosity=Unspecified (PubMed=1576714).
- Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
- Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
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| Species of origin |
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
(NCBI Taxonomy: 10029) |
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| Hierarchy |
Parent: CVCL_2234 (V79) |
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| Sex of cell |
Male |
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| Age at sampling |
Adult |
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| Category |
Spontaneously immortalized cell line |
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| Publications | PubMed=2471930; DOI=10.1016/0027-5107(89)90076-6
Zhang L.-H., Jenssen D.
Isolation and characterization of spontaneously occurring mutations at the HPRT locus in V79 Chinese hamster cells.
Mutat. Res. 212:253-262(1989) PubMed=1576714; DOI=10.1093/carcin/13.4.609
Zhang L.-H., Jenssen D.
Reversion of the hprt mutant clone SP5 by intrachromosomal recombination.
Carcinogenesis 13:609-615(1992) PubMed=7955071; DOI=10.1093/carcin/15.10.2303
Zhang L.-H., Jenssen D.
Studies on intrachromosomal recombination in SP5/V79 Chinese hamster cells upon exposure to different agents related to carcinogenesis.
Carcinogenesis 15:2303-2310(1994) PubMed=8914605; DOI=10.1007/BF02369910
Dare E., Zhang L.-H., Jenssen D.
Characterization of mutants involving partial exon duplications in the hprt gene of Chinese hamster V79 cells.
Somat. Cell Mol. Genet. 22:201-210(1996) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54992579
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| Entry history |
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| Entry creation | 05-Mar-2018 |
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| Last entry update | 29-Jun-2023 |
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| Version number | 9 |
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