ID   V79 SP5
AC   CVCL_RW41
SY   V79 Sp5; V79/SP5; SP5; Sp5; SP5/V79
DR   Wikidata; Q54992579
RX   PubMed=1576714;
RX   PubMed=2471930;
RX   PubMed=7955071;
RX   PubMed=8914605;
CC   Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
CC   Sequence variation: Mutation; UniProtKB; P00494; Hprt1; Unexplicit; Ex2dup; Zygosity=Unspecified (PubMed=1576714).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_2234 ! V79
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 05-03-18; Last updated: 29-06-23; Version: 9
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RX   PubMed=1576714; DOI=10.1093/carcin/13.4.609;
RA   Zhang L.-H., Jenssen D.;
RT   "Reversion of the hprt mutant clone SP5 by intrachromosomal
RT   recombination.";
RL   Carcinogenesis 13:609-615(1992).
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RX   PubMed=2471930; DOI=10.1016/0027-5107(89)90076-6;
RA   Zhang L.-H., Jenssen D.;
RT   "Isolation and characterization of spontaneously occurring mutations
RT   at the HPRT locus in V79 Chinese hamster cells.";
RL   Mutat. Res. 212:253-262(1989).
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RX   PubMed=7955071; DOI=10.1093/carcin/15.10.2303;
RA   Zhang L.-H., Jenssen D.;
RT   "Studies on intrachromosomal recombination in SP5/V79 Chinese hamster
RT   cells upon exposure to different agents related to carcinogenesis.";
RL   Carcinogenesis 15:2303-2310(1994).
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RX   PubMed=8914605; DOI=10.1007/BF02369910;
RA   Dare E., Zhang L.-H., Jenssen D.;
RT   "Characterization of mutants involving partial exon duplications in
RT   the hprt gene of Chinese hamster V79 cells.";
RL   Somat. Cell Mol. Genet. 22:201-210(1996).
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