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Cellosaurus V79 SPD8 (CVCL_RW42)

[Text version]
Cell line name V79 SPD8
Synonyms V79/SPD8; V79(SPD8); SPD8; SPD8/V79
Accession CVCL_RW42
Resource Identification Initiative To cite this cell line use: V79 SPD8 (RRID:CVCL_RW42)
Comments Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; P00494; Hprt1; Unexplicit; Ex7dup; Zygosity=Unspecified (PubMed=8914605).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_2234 (V79)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=8914605; DOI=10.1007/BF02369910
Dare E., Zhang L.-H., Jenssen D.
Characterization of mutants involving partial exon duplications in the hprt gene of Chinese hamster V79 cells.
Somat. Cell Mol. Genet. 22:201-210(1996)

PubMed=9642052; DOI=10.1006/jmbi.1998.1809
Helleday T., Arnaudeau C., Jenssen D.
A partial hprt gene duplication generated by non-homologous recombination in V79 Chinese hamster cells is eliminated by homologous recombination.
J. Mol. Biol. 279:687-694(1998)

PubMed=10373364; DOI=10.1006/jmbi.1999.2856
Arnaudeau C., Helleday T., Jenssen D.
The RAD51 protein supports homologous recombination by an exchange mechanism in mammalian cells.
J. Mol. Biol. 289:1231-1238(1999)

Cross-references
Encyclopedic resources Wikidata; Q54992582
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number9