ID   V79 SPD8
AC   CVCL_RW42
SY   V79/SPD8; V79(SPD8); SPD8; SPD8/V79
DR   Wikidata; Q54992582
RX   PubMed=8914605;
RX   PubMed=9642052;
RX   PubMed=10373364;
CC   Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
CC   Sequence variation: Mutation; UniProtKB; P00494; Hprt1; Unexplicit; Ex7dup; Zygosity=Unspecified (PubMed=8914605).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_2234 ! V79
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 05-03-18; Last updated: 29-06-23; Version: 9
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RX   PubMed=8914605; DOI=10.1007/BF02369910;
RA   Dare E., Zhang L.-H., Jenssen D.;
RT   "Characterization of mutants involving partial exon duplications in
RT   the hprt gene of Chinese hamster V79 cells.";
RL   Somat. Cell Mol. Genet. 22:201-210(1996).
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RX   PubMed=9642052; DOI=10.1006/jmbi.1998.1809;
RA   Helleday T., Arnaudeau C., Jenssen D.;
RT   "A partial hprt gene duplication generated by non-homologous
RT   recombination in V79 Chinese hamster cells is eliminated by
RT   homologous recombination.";
RL   J. Mol. Biol. 279:687-694(1998).
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RX   PubMed=10373364; DOI=10.1006/jmbi.1999.2856;
RA   Arnaudeau C., Helleday T., Jenssen D.;
RT   "The RAD51 protein supports homologous recombination by an exchange
RT   mechanism in mammalian cells.";
RL   J. Mol. Biol. 289:1231-1238(1999).
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