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Cellosaurus HG23 (CVCL_RW46)

[Text version]

Cell line name HG23
Accession CVCL_RW46
Resource Identification Initiative To cite this cell line use: HG23 (RRID:CVCL_RW46)
Comments Population: Japanese.
Characteristics: Stably transfected with plasmid NV101, which contains a cloned cDNA consensus sequence of the RNA genome of Norwalk virus.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Sequence variations Homozygous for KDR p.Gln472His (c.1416A>T) (from parent cell line).
POLD3 p.Lys70Arg (c.209A>G) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Homozygous for TP53 p.Tyr220Cys (c.659A>G) (ClinVar=VCV000127819) (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0336 (Huh-7)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
Publications

PubMed=16843517; DOI=10.1016/j.virol.2006.06.006
Chang K.-O., Sosnovtsev S.V., Belliot G., King A.D., Green K.Y.
Stable expression of a Norwalk virus RNA replicon in a human hepatoma cell line.
Virology 353:463-473(2006)

PubMed=19515767; DOI=10.1128/JVI.00005-09
Chang K.-O.
Role of cholesterol pathways in norovirus replication.
J. Virol. 83:8587-8595(2009)

Cross-references
Gene expression databases GEO; GSM388886
GEO; GSM388887
GEO; GSM388888
Other Wikidata; Q54885923
Entry history
Entry creation05-Mar-2018
Last entry update02-Jul-2020
Version number4