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Cellosaurus HepJ5 (CVCL_RW48)

[Text version]

Cell line name HepJ5
Synonyms Hep-J5; Hep J5
Accession CVCL_RW48
Resource Identification Initiative To cite this cell line use: HepJ5 (RRID:CVCL_RW48)
Comments Population: Caucasian.
Characteristics: GRP78-overexpressing.
Derived from sampling site: Liver.
Sequence variations Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line

PubMed=19830497; DOI=10.1245/s10434-009-0718-8
Chiou J.-F., Tai C.-J., Huang M.-T., Wei P.-L., Wang Y.-H., An J., Wu C.-H., Liu T.-Z., Chang Y.-J.
Glucose-regulated protein 78 is a novel contributor to acquisition of resistance to sorafenib in hepatocellular carcinoma.
Ann. Surg. Oncol. 17:603-612(2010)

PubMed=20087778; DOI=10.1245/s10434-010-0912-8
Chang Y.-J., Chiu C.-C., Wu C.-H., An J., Wu C.-C., Liu T.-Z., Wei P.-L., Huang M.-T.
Glucose-regulated protein 78 (GRP78) silencing enhances cell migration but does not influence cell proliferation in hepatocellular carcinoma.
Ann. Surg. Oncol. 17:1703-1709(2010)

Other Wikidata; Q54882869
Entry history
Entry creation05-Mar-2018
Last entry update20-May-2021
Version number8