ID   HepJ5
AC   CVCL_RW48
SY   Hep-J5; Hep J5
DR   Wikidata; Q54882869
RX   PubMed=19830497;
RX   PubMed=20087778;
CC   Population: Caucasian.
CC   Characteristics: GRP78-overexpressing.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Derived from sampling site: Liver.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 20-05-21; Version: 8
//
RX   PubMed=19830497; DOI=10.1245/s10434-009-0718-8;
RA   Chiou J.-F., Tai C.-J., Huang M.-T., Wei P.-L., Wang Y.-H., An J.,
RA   Wu C.-H., Liu T.-Z., Chang Y.-J.;
RT   "Glucose-regulated protein 78 is a novel contributor to acquisition of
RT   resistance to sorafenib in hepatocellular carcinoma.";
RL   Ann. Surg. Oncol. 17:603-612(2010).
//
RX   PubMed=20087778; DOI=10.1245/s10434-010-0912-8;
RA   Chang Y.-J., Chiu C.-C., Wu C.-H., An J., Wu C.-C., Liu T.-Z.,
RA   Wei P.-L., Huang M.-T.;
RT   "Glucose-regulated protein 78 (GRP78) silencing enhances cell
RT   migration but does not influence cell proliferation in hepatocellular
RT   carcinoma.";
RL   Ann. Surg. Oncol. 17:1703-1709(2010).
//