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Cellosaurus RG37 (CVCL_RW59)

[Text version]
Cell line name RG37
Accession CVCL_RW59
Resource Identification Initiative To cite this cell line use: RG37 (RRID:CVCL_RW59)
Comments Population: African American.
Characteristics: Transfected with the DR-GFP construct which contains a tandem repeat of two inactive genes coding for EGFP. After transfection with an expression vector coding for the I-SceI enzyme, recombination induced by the cleavage of the I-SceI site recreates a functional EGFP.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Galactosemia (NCIt: C84723)
Galactosemia (ORDO: Orphanet_352)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7299 (GM00639)
Sex of cell Male
Age at sampling 15Y
Category Transformed cell line
Publications

PubMed=16407825; DOI=10.1038/sj.onc.1209344
Dumay A., Laulier C., Bertrand P., Saintigny Y., Lebrun F., Vayssiere J.L., Lopez B.S.
Bax and Bid, two proapoptotic Bcl-2 family members, inhibit homologous recombination, independently of apoptosis regulation.
Oncogene 25:3196-3205(2006)

Cross-references
Encyclopedic resources Wikidata; Q54950243
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number6