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Cellosaurus P7731 (CVCL_RY01)

[Text version]
Cell line name P7731
Accession CVCL_RY01
Resource Identification Initiative To cite this cell line use: P7731 (RRID:CVCL_RY01)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Doubling time: ~24 hours (Direct_author_submission).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Miscellaneous: Doubling time and age of donor from personal communication of Chenevix-Trench G.
Miscellaneous: Conflicts in the STR profile of markers TH01 and vWA between PubMed=28889351 and PubMed=29468485 are clerical errors and are thus not recorded in the relevant section (personal communication of Chenevix-Trench G.).
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 40Y
Category Cancer cell line
STR profile Source(s): PubMed=28889351; PubMed=29468485

Markers:
AmelogeninX
CSF1PO13,14
D5S8189
D7S8208,11
D13S31711,12
D16S53911
D21S1131,31.2
TH018,9.3
TPOX8,9
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=28889351; DOI=10.1007/s10549-017-4496-x
Saunus J.M., Smart C.E., Kutasovic J.R., Johnston R.L., Kalita-de Croft P., Miranda M., Rozali E.N., Vargas A.C., Reid L.E., Lorsy E., Cocciardi S., Seidens T., McCart Reed A.E., Dalley A.J., Wockner L.F., Johnson J., Sarkar D., Askarian-Amiri M.E., Simpson P.T., Khanna K.K., Chenevix-Trench G., Al-Ejeh F., Lakhani S.R.
Multidimensional phenotyping of breast cancer cell lines to guide preclinical research.
Breast Cancer Res. Treat. 167:289-301(2018)

PubMed=29468485; DOI=10.1007/s10549-018-4719-9
Johnson J., Bessette D.C., Saunus J.M., Smart C.E., Song S., Johnston R.L., Cocciardi S., Rozali E.N., Johnstone C.N., Vargas A.C., Kazakoff S.H., Khanna K.K., Lakhani S.R., Chenevix-Trench G., Simpson P.T., Nones K., Waddell N., Al-Ejeh F.
Characterization of a novel breast cancer cell line derived from a metastatic bone lesion of a breast cancer patient.
Breast Cancer Res. Treat. 170:179-188(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RY01
Encyclopedic resources Wikidata; Q54937316
Gene expression databases GEO; GSM2769404
GEO; GSM2769405
GEO; GSM2769406
GEO; GSM2785715
Polymorphism and mutation databases Cosmic; 2814455
Sequence databases EGA; EGAS00001002840
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number10