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Cellosaurus HaCaT SimpleCell O-GalNAc (CVCL_S024)

[Text version]
Cell line name HaCaT SimpleCell O-GalNAc
Synonyms HaCaT SimpleCell; HaCaT SC; Cosmc KO HaCaT
Accession CVCL_S024
Resource Identification Initiative To cite this cell line use: HaCaT SimpleCell O-GalNAc (RRID:CVCL_S024)
Comments Population: Caucasian.
Characteristics: Cell engineered to produce only truncated GalNAc or NeuAc-alpha-2-6-GalNAc O-glycans.
Knockout cell: Method=ZFN; HGNC; 24338; C1GALT1C1.
Derived from site: In situ; Back, skin, epidermis; UBERON=UBERON_0001068+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg282Trp (c.843_844CC>TT); Zygosity=Heterozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0038 (HaCaT)
Sex of cell Male
Age at sampling 62Y
Category Spontaneously immortalized cell line
Publications

PubMed=23584533; DOI=10.1038/emboj.2013.79
Steentoft C., Vakhrushev S.Y., Joshi H.J., Kong Y., Vester-Christensen M.B., Schjoldager K.T.-B.G., Lavrsen K., Dabelsteen S., Pedersen N.B., Marcos-Silva L., Gupta R., Bennett E.P., Mandel U., Brunak S., Wandall H.H., Levery S.B., Clausen H.
Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology.
EMBO J. 32:1478-1488(2013)

Cross-references
Encyclopedic resources Wikidata; Q54872314
Entry history
Entry creation05-Nov-2013
Last entry update29-Jun-2023
Version number15