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Cellosaurus KC (CVCL_S097)

[Text version]

Cell line name KC
Synonyms KC-R; KC RAND
Accession CVCL_S097
Resource Identification Initiative To cite this cell line use: KC (RRID:CVCL_S097)
Comments Problematic cell line: Contaminated. Parent cell line (U-118MG) has been shown to be a U-138MG derivative.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Sequence variations Homozygous for PTEN c.1026+1G>T (IVS8+1G>T) (ClinVar=VCV000635377); Note=Splice donor mutation (from parent cell line).
Homozygous for TP53 p.Arg213Gln (c.638G>A) (ClinVar=VCV000135359) (from parent cell line).
Disease Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0633 (U-118MG)
Sex of cell Male
Age at sampling 47Y
Category Cancer cell line
Publications

PubMed=4313504; DOI=10.1111/j.1699-0463.1968.tb03502.x
Ponten J., Macintyre E.H.
Long term culture of normal and neoplastic human glia.
Acta Pathol. Microbiol. Scand. 74:465-486(1968)

PubMed=4351391; DOI=10.1093/jnci/50.5.1129
Nelson-Rees W.A., Klement V., Peterson W.D. Jr., Weaver J.F.
Comparative study of two RD 114 virus-indicator cell lines, KC and KB.
J. Natl. Cancer Inst. 50:1129-1135(1973)

PubMed=6500159; DOI=10.1159/000163283
Gershwin M.E., Lentz D., Owens R.B.
Relationship between karyotype of tissue culture lines and tumorigenicity in nude mice.
Exp. Cell Biol. 52:361-370(1984)

Cross-references
Cell line collections ATCC; CRL-7719 - Discontinued
Other Wikidata; Q54899591
Entry history
Entry creation05-Nov-2013
Last entry update12-Jan-2021
Version number13