Cellosaurus cell line CHO irs-20 (CVCL_S167)

• Mutation; UniProtKB; A0A061I8A6; Prkdc; Simple; p.Glu4090Lys (c.11268G>A); Zygosity=Heterozygous (PubMed=9518490).
  

PubMed=7504309; DOI=10.2307/3578617
Stackhouse M.A., Bedford J.S.
An ionizing radiation-sensitive mutant of CHO cells: irs-20. I Isolation and initial characterization.
Radiat. Res. 136:241-249(1993)

PubMed=8248482; DOI=10.2307/3578618
Stackhouse M.A., Bedford J.S.
An ionizing radiation-sensitive mutant of CHO cells: irs-20. II Dose-rate effects and cellular recovery processes.
Radiat. Res. 136:250-254(1993)

PubMed=7910196; DOI=10.1080/09553009414550661
Stackhouse M.A., Bedford J.S.
An ionizing radiation-sensitive mutant of CHO cells: irs-20. III Chromosome aberrations, DNA breaks and mitotic delay.
Int. J. Radiat. Biol. 65:571-582(1994)

PubMed=9008208; DOI=10.2307/3579417
Lin J.Y.-D., Muhlmann-Diaz M.C., Stackhouse M.A., Robinson J.F., Taccioli G.E., Chen D.J., Bedford J.S.
An ionizing radiation-sensitive CHO mutant cell line: irs-20. IV Genetic complementation, V(D)J recombination and the scid phenotype.
Radiat. Res. 147:166-171(1997)

PubMed=9518490; DOI=10.1093/nar/26.8.1965
Priestley A., Beamish H.J., Gell D., Amatucci A.G., Muhlmann-Diaz M.C., Singleton B.K., Smith G.C.M., Blunt T., Schalkwyk L.C., Bedford J.S., Jackson S.P., Jeggo P.A., Taccioli G.E.
Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20.
Nucleic Acids Res. 26:1965-1973(1998)