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Cellosaurus MSC 80 (CVCL_S187)

[Text version]
Cell line name MSC 80
Synonyms MSC-80; MSC80; Mouse Schwann Cell line 80
Accession CVCL_S187
Resource Identification Initiative To cite this cell line use: MSC 80 (RRID:CVCL_S187)
Comments Characteristics: Can be infected in vitro with mouse scrapie prion (PrPSc) and will continue to produce PrPSc after 18 passages and is able to transmit the prion disease to mice.
Doubling time: 17 hours (PubMed=1629940).
Omics: Cell surface proteome.
Derived from site: In situ; Peripheral nervous system, sciatic nerve; UBERON=UBERON_0001322.
Cell type: Schwann cell; CL=CL_0002573.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 x DBA/2.
Category Spontaneously immortalized cell line
Publications

PubMed=1629940; DOI=10.1002/jnr.490320103
Boutry J.-M., Hauw J.-J., Gansmuller A., Di-Bert N., Pouchelet M., Baron-Van Evercooren A.
Establishment and characterization of a mouse Schwann cell line which produces myelin in vivo.
J. Neurosci. Res. 32:15-26(1992)

PubMed=11836421; DOI=10.1128/JVI.76.5.2434-2439.2002
Follet J., Lemaire-Vieille C., Blanquet-Grossard F., Podevin-Dimster V., Lehmann S., Chauvin J.-P., Decavel J.-P., Varea R., Grassi J., Fontes M., Cesbron J.-Y.
PrP expression and replication by Schwann cells: implications in prion spreading.
J. Virol. 76:2434-2439(2002)

Patent=US7001767
Blanquet-Grossard F., Cesbron J.-Y., Lemaire-Vieille C., Follet J.
Method for in vitro propagation of the agent responsible for transmissible spongiform encephalopathies.
Patent number US7001767, 21-Feb-2006

PubMed=25894527; DOI=10.1371/journal.pone.0121314
Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F., Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R., Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P., Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B.
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:E0121314-E0121314(2015)

Cross-references
Encyclopedic resources Wikidata; Q54906813
Proteomic databases PRIDE; PXD000589
Entry history
Entry creation05-Nov-2013
Last entry update29-Jun-2023
Version number9