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Cellosaurus MOLT-4/CCR5 (CVCL_S545)

Cell line name MOLT-4/CCR5
Synonyms MOLT-4 CCR5+
Accession CVCL_S545
Resource Identification Initiative To cite this cell line use: MOLT-4/CCR5 (RRID:CVCL_S545)
Comments Transfected with: HGNC; 1606; CCR5.
Derived from sampling site: Peripheral blood.
Sequence variations Heterozygous for NRAS p.Gly12Cys (c.34G>T) (from parent cell line).
Homozygous for PTEN p.Lys267fs*9 (c.800delA) (from parent cell line).
Heterozygous for STK11 p.Gln214Ter (c.640C>T) (from parent cell line).
Heterozygous for TP53 p.Arg306Ter (c.916C>T) (from parent cell line).
Disease Adult T acute lymphoblastic leukemia (NCIt: C9142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F827 (MOLT-4 clone 8)
Children:
CVCL_0C87 (MOCHA)
Sex of cell Male
Age at sampling 19Y
Category Cancer cell line
Publications

PubMed=10890354; DOI=10.1089/08892220050058344
Baba M., Miyake H., Okamoto M., Iizawa Y., Okonogi K.
Establishment of a CCR5-expressing T-lymphoblastoid cell line highly susceptible to R5 HIV type 1.
AIDS Res. Hum. Retroviruses 16:935-941(2000)

Cross-references
Cell line collections NIH-ARP; 4984-447
Other Wikidata; Q54906369