Cellosaurus MOLT-4/CCR5 (CVCL_S545)

Cell line name MOLT-4/CCR5
Synonyms MOLT-4 CCR5+
Accession CVCL_S545
Resource Identification Initiative To cite this cell line use: MOLT-4/CCR5 (RRID:CVCL_S545)
Comments Sequence variation: Heterozygous for NRAS p.Gly12Cys (from parent cell line).
Sequence variation: Homozygous for PTEN p.Lys267fs*9 (from parent cell line).
Sequence variation: Heterozygous for STK11 p.Gln214Ter (from parent cell line).
Sequence variation: Heterozygous for TP53 p.Arg306Ter (from parent cell line).
Transfected with: HGNC; 1606; CCR5.
Derived from sampling site: Peripheral blood.
Disease Adult T acute lymphoblastic leukemia (NCIt: C9142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F827 (MOLT-4 clone 8)
Sex of cell Male
Category Cancer cell line

PubMed=10890354; DOI=10.1089/08892220050058344
Baba M., Miyake H., Okamoto M., Iizawa Y., Okonogi K.
Establishment of a CCR5-expressing T-lymphoblastoid cell line highly susceptible to R5 HIV type 1.
AIDS Res. Hum. Retroviruses 16:935-941(2000)

Cell line collections NIH-ARP; 4984-447