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Cellosaurus K562/ZD1694.C (CVCL_S663)

[Text version]

Cell line name K562/ZD1694.C
Synonyms K562/ZD1694 x C
Accession CVCL_S663
Resource Identification Initiative To cite this cell line use: K562/ZD1694.C (RRID:CVCL_S663)
Comments Selected for resistance to: ChEBI; CHEBI:5847; ICI D1694 (Tomudex; ZD1694).
Derived from sampling site: Pleural effusion.
Sequence variations BCR-ABL1 gene fusion (from parent cell line).
Homozygous for TP53 p.Gln136fs*13 (c.406_407insC) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line

PubMed=8576277; DOI=10.1007/BF01226268
Takemura Y., Gibson W., Kimbell R., Kobayashi H., Miyachi H., Jackman A.L.
Cellular pharmacokinetics of ZD1694 in cultured human leukaemia cells sensitive, or made resistant, to this drug.
J. Cancer Res. Clin. Oncol. 122:109-117(1996)

Other Wikidata; Q54899419
Entry history
Entry creation03-Feb-2014
Last entry update12-Mar-2020
Version number11