ID   M980513
AC   CVCL_S675
DR   cancercelllines; CVCL_S675
DR   Cell_Model_Passport; SIDM00177
DR   Cosmic; 1723794
DR   DepMap; ACH-002338
DR   GEO; GSM108371
DR   GEO; GSM108382
DR   GEO; GSM4933088
DR   PharmacoDB; M980513_880_2019
DR   Wikidata; Q54903663
RX   PubMed=16827748;
RX   PubMed=18245463;
RX   PubMed=22336146;
RX   PubMed=33445472;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   From: URPP Biobank, University of Zurich; Zurich; Switzerland.
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=16827748; DepMap).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Miscellaneous: Age/sex of donor and metastatic site from personal communication of URPP Biobank.
CC   Derived from site: Metastatic; Iliac lymph node; UBERON=UBERON_0015878.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   32Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 05-10-23; Version: 19
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RX   PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x;
RA   Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R.,
RA   Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D.,
RA   Dummer R.;
RT   "Metastatic potential of melanomas defined by specific gene expression
RT   profiles with no BRAF signature.";
RL   Pigment Cell Res. 19:290-302(2006).
//
RX   PubMed=18245463; DOI=10.1158/0008-5472.CAN-07-2491;
RA   Hoek K.S., Eichhoff O.M., Schlegel N.C., Dobbeling U., Kobert N.,
RA   Schaerer L., Hemmi S., Dummer R.;
RT   "In vivo switching of human melanoma cells between proliferative and
RT   invasive states.";
RL   Cancer Res. 68:650-656(2008).
//
RX   PubMed=22336146; DOI=10.1111/j.1755-148X.2012.00986.x;
RA   Widmer D.S., Cheng P.F., Eichhoff O.M., Belloni B.C., Zipser M.C.,
RA   Schlegel N.C., Javelaud D., Mauviel A., Dummer R., Hoek K.S.;
RT   "Systematic classification of melanoma cells by phenotype-specific
RT   gene expression mapping.";
RL   Pigment Cell Melanoma Res. 25:343-353(2012).
//
RX   PubMed=33445472; DOI=10.3390/ncrna7010005;
RA   Tusup M., Cheng P.F., Picardi E., Raziunaite A., Dummer R.,
RA   Levesque M.P., French L.E., Guenova E., Kundig T.M., Pascolo S.;
RT   "Evaluation of the interplay between the ADAR editome and
RT   immunotherapy in melanoma.";
RL   Noncoding RNA 7:5.1-5.11(2021).
//