Cellosaurus HCC4011 (CVCL_S700)

Cell line name HCC4011
Accession CVCL_S700
Resource Identification Initiative To cite this cell line use: HCC4011 (RRID:CVCL_S700)
Comments Part of: MD Anderson Cell Lines Project.
Sequence variation: EGFR p.Leu858Arg.
Omics: Deep RNAseq analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_S701 (HCC4011-GR-high); CVCL_S702 (HCC4011-GR-step); CVCL_S747 (HCC4011/R)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=20679594; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO12,14
D13S31712
D16S5398,11
D18S5119,20
D21S1131,31.2
D3S135818
D5S81812,13
D7S8209,10
D8S117911,13
FGA19,20
Penta D12,14
Penta E17
TH016
TPOX11
vWA16,17
Web pages http://www.utsouthwestern.edu/edumedia/edufiles/about_us/admin_offices/technology_development/available_technologies/cell-lines.pdf
http://tcpaportal.org/mclp/
Publications

PubMed=20679594; DOI=10.1093/jnci/djq279
Gazdar A.F., Girard L., Lockwood W.W., Lam W.L., Minna J.D.
Lung cancer cell lines as tools for biomedical discovery and research.
J. Natl. Cancer Inst. 102:1310-1321(2010)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Ontologies EFO; EFO_0006436
Biological sample resources BioSample; SAMN03473004
Gene expression databases GEO; GSM794400