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Cellosaurus HEC-1C (CVCL_S835)

[Text version]
Cell line name HEC-1C
Synonyms HEC-1 C; HEC-IC
Accession CVCL_S835
Resource Identification Initiative To cite this cell line use: HEC-1C (RRID:CVCL_S835)
Comments Population: Japanese.
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7329; MSH6; Simple; c.4001+1G>T; ClinVar=VCV001736936; Zygosity=Heterozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; 9122; PMS2; Simple; p.Arg802Ter (c.2404C>T); ClinVar=VCV000009237; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Endometrial adenocarcinoma (NCIt: C7359)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1274 (HEC-1)
Sex of cell Female
Age at sampling 71Y
Category Cancer cell line
Publications

PubMed=6299971; DOI=10.1002/ijc.2910310105
Morinaga N., Yonehara S., Tomita Y., Kuwata T.
Insensitivity to interferon of two subclones of human endometrial carcinoma cell line, HEC-1.
Int. J. Cancer 31:21-28(1983)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S835
Encyclopedic resources Wikidata; Q54882259
Entry history
Entry creation03-Feb-2014
Last entry update05-Oct-2023
Version number16