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Cellosaurus HROC24 (CVCL_S853)

[Text version]
Cell line name HROC24
Synonyms HROC24P
Accession CVCL_S853
Resource Identification Initiative To cite this cell line use: HROC24 (RRID:CVCL_S853)
Comments From: Linnebacher M.; University of Rostock; Rostock; Germany.
Population: Caucasian.
Microsatellite instability: Instable (MSI) (PubMed=25926053).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
HLA typing Source: Direct_author_submission
Class I
HLA-AA*02:01,30:02
HLA-BB*18:01,38:01
HLA-CC*05:01,12:03
Class II
HLA-DQDQB1*02:01,06:01
HLA-DRDRB1*03:01,13:01
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_YD57 ! B-LCL-HROC24
CVCL_1U80 ! HROC24 T1 M1
CVCL_AN14 ! HROC24 T3 M1 #2
Sex of cell Male
Age at sampling 98Y
Category Cancer cell line
STR profile Source(s): CLS; Direct_author_submission; PubMed=25926053

Markers:
AmelogeninX,Y
CSF1PO10,11 (Direct_author_submission)
11,12 (CLS; PubMed=25926053)
D5S81810,11 (CLS; PubMed=25926053)
10,12 (Direct_author_submission)
D7S82011,13
D13S3177 (Direct_author_submission)
7,13 (CLS; PubMed=25926053)
D16S5399,11
D21S1127,28
TH016,9
TPOX11
vWA16,20 (CLS; PubMed=25926053)
16,21 (Direct_author_submission)

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Publications

PubMed=23300683; DOI=10.1371/journal.pone.0052485
Maletzki C., Stier S., Gruenert U., Gock M., Ostwald C., Prall F., Linnebacher M.
Establishment, characterization and chemosensitivity of three mismatch repair deficient cell lines from sporadic and inherited colorectal carcinomas.
PLoS ONE 7:E52485-E52485(2012)

PubMed=25309914; DOI=10.1155/2014/568693
Lange F., Franz B., Maletzki C., Linnebacher M., Huhns M., Jaster R.
Biological and molecular effects of small molecule kinase inhibitors on low-passage human colorectal cancer cell lines.
BioMed Res. Int. 2014:568693.1-568693.13(2014)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

PubMed=31601052; DOI=10.3390/cancers11101520
Mullins C.S., Micheel B., Matschos S., Leuchter M., Burtin F., Krohn M., Huhns M., Klar E., Prall F., Linnebacher M.
Integrated biobanking and tumor model establishment of human colorectal carcinoma provides excellent tools for preclinical research.
Cancers (Basel) 11:1520.1-1520.18(2019)

Cross-references
Cell line collections (Providers) CLS; 300812
Encyclopedic resources Wikidata; Q54895254
Gene expression databases GEO; GSM1448071
Entry history
Entry creation03-Feb-2014
Last entry update29-Jun-2023
Version number20