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Cellosaurus TC71 (CVCL_S882)

[Text version]

Cell line name TC71
Accession CVCL_S882
Resource Identification Initiative To cite this cell line use: TC71 (RRID:CVCL_S882)
Comments Microsatellite instability: Instable (MSI) (PubMed=9000572; PubMed=24042735; PubMed=28683746).
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Miscellaneous: STR profile mentioned but not shown in PubMed=24042735; obtained by personal communication of Lind G.E.
Sequence variations KRAS p.Gly12Asp (c.35G>A) (PubMed=20570890; PubMed=28683746).
PTEN p.Arg233Ter (c.697C>T) (PubMed=28683746).
TP53 p.Cys176Tyr (c.527G>A) and p.Arg213Ter (c.637C>T) (PubMed=28683746).
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): PubMed=24042735

Markers:
AmelogeninX
CSF1PO10,15
D2S133816,17
D3S135815
D5S81810,12
D7S82012
D8S117910,13
D13S3179,12,13
D16S53911
D18S5110,11,15
D19S43313
D21S1129,32.2
FGA18,19
TH017,8
TPOX9,11
vWA14,17

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Publications

PubMed=9000572
Hoang J.-M., Cottu P.H., Thuille B., Salmon R.J., Thomas G., Hamelin R.
BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines.
Cancer Res. 57:300-303(1997)

PubMed=10732766; DOI=10.1054/bjoc.1999.1019
Bras-Goncalves R.A., Rosty C., Laurent-Puig P., Soulie P., Dutrillaux B., Poupon M.-F.
Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status.
Br. J. Cancer 82:913-923(2000)

PubMed=11526487; DOI=10.1038/sj.onc.1204611
Gayet J., Zhou X.-P., Duval A., Rolland S., Hoang J.-M., Cottu P.H., Hamelin R.
Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.
Oncogene 20:5025-5032(2001)

PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192
Janakiraman M., Vakiani E., Zeng Z., Pratilas C.A., Taylor B.S., Chitale D., Halilovic E., Wilson M., Huberman K., Ricarte Filho J.C., Persaud Y., Levine D.A., Fagin J.A., Jhanwar S.C., Mariadason J.M., Lash A., Ladanyi M., Saltz L.B., Heguy A., Paty P.B., Solit D.B.
Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
Cancer Res. 70:5901-5911(2010)

PubMed=24042735; DOI=10.1038/oncsis.2013.35
Ahmed D., Eide P.W., Eilertsen I.A., Danielsen S.A., Eknaes M., Hektoen M., Lind G.E., Lothe R.A.
Epigenetic and genetic features of 24 colon cancer cell lines.
Oncogenesis 2:E71-E71(2013)

PubMed=28683746; DOI=10.1186/s12943-017-0691-y
Berg K.C.G., Eide P.W., Eilertsen I.A., Johannessen B., Bruun J., Danielsen S.A., Bjornslett M., Meza-Zepeda L.A., Eknaes M., Lind G.E., Myklebost O., Skotheim R.I., Sveen A., Lothe R.A.
Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies.
Mol. Cancer 16:116-116(2017)

Cross-references
Cell line databases/resources ColonAtlas; TC71
Gene expression databases GEO; GSM2550020
Other Wikidata; Q54971843
Polymorphism and mutation databases Cosmic; 711259
Cosmic; 887221
Cosmic; 1132567
Cosmic; 1479584
Entry history
Entry creation03-Feb-2014
Last entry updated07-Sep-2018
Version number9