Cellosaurus C170 (CVCL_S959)

Cell line name C170
Accession CVCL_S959
Resource Identification Initiative To cite this cell line use: C170 (RRID:CVCL_S959)
Comments Doubling time: 26 +- 0.5 hours (PubMed=3947514).
Microsatellite instability: Instable (MSI) (PubMed=25926053).
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Colorectal adenocarcinoma (NCIt: C5105)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO12
D13S3178,11
D16S53912,13
D18S5111,17
D21S1129,32.2
D3S135817
D5S81813
D7S82010,12
D8S117915
FGA22
Penta D9,14
Penta E7,14
TH017,9.3
TPOX8,11
vWA18,19
Publications

PubMed=3947514; DOI=10.1038/bjc.1986.6
Durrant L.G., Robins R.A., Pimm M.V., Perkins A.C., Armitage N.C., Hardcastle J.D., Baldwin R.W.
Antigenicity of newly established colorectal carcinoma cell lines.
Br. J. Cancer 53:37-45(1986)

PubMed=3435698; DOI=10.1038/bjc.1987.277
Durrant L.G., Garnett M.C., Gallego J., Armitage N.C., Ballantyne K.C., Marksman R.A., Hardcastle J.D., Baldwin R.W.
Sensitivity of newly established colorectal cell lines to cytotoxic drugs and monoclonal antibody drug conjugates.
Br. J. Cancer 56:722-726(1987)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002-7002(2015)

Cross-references
Cell line databases/resources ColonAtlas; C170
LINCS_LDP; LCL-1156
Ontologies EFO; EFO_0006363
Biological sample resources BioSample; SAMN03473189
Chemistry resources ChEMBL-Cells; CHEMBL3308628
ChEMBL-Targets; CHEMBL614705
Gene expression databases GEO; GSM206448
GEO; GSM274834
GEO; GSM513927
GEO; GSM514181
GEO; GSM827320
GEO; GSM1448107