ID   C170
AC   CVCL_S959
DR   CLO; CLO_0009954
DR   EFO; EFO_0006363
DR   ArrayExpress; E-MTAB-2706
DR   BioSample; SAMN03473189
DR   cancercelllines; CVCL_S959
DR   ChEMBL-Cells; CHEMBL3308628
DR   ChEMBL-Targets; CHEMBL614705
DR   ColonAtlas; C170
DR   EGA; EGAS00001000610
DR   GEO; GSM206448
DR   GEO; GSM274834
DR   GEO; GSM513927
DR   GEO; GSM514181
DR   GEO; GSM827320
DR   GEO; GSM1448107
DR   LINCS_LDP; LCL-1156
DR   PharmacoDB; C170_152_2019
DR   Progenetix; CVCL_S959
DR   PubChem_Cell_line; CVCL_S959
DR   Wikidata; Q54807871
RX   PubMed=3435698;
RX   PubMed=3947514;
RX   PubMed=20215515;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=25926053;
RX   PubMed=26589293;
CC   Doubling time: 26 +- 0.5 hours (PubMed=3947514).
CC   HLA typing: A*02:01,24:02; B*08:01,35:01; C*04:01,07:01 (PubMed=26589293).
CC   Microsatellite instability: Instable (MSI) (PubMed=25926053).
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
ST   Source(s): PubMed=25877200; PubMed=25926053
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 8,11
ST   D16S539: 12,13
ST   D18S51: 11,17
ST   D21S11: 29,32.2
ST   D3S1358: 17
ST   D5S818: 13
ST   D7S820: 10,12
ST   D8S1179: 15
ST   FGA: 22
ST   Penta D: 9,14
ST   Penta E: 7,14
ST   TH01: 7,9.3
ST   TPOX: 8,11
ST   vWA: 18,19
DI   NCIt; C5105; Colorectal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 05-10-23; Version: 22
//
RX   PubMed=3435698; DOI=10.1038/bjc.1987.277;
RA   Durrant L.G., Garnett M.C., Gallego J., Armitage N.C.,
RA   Ballantyne K.C., Marksman R.A., Hardcastle J.D., Baldwin R.W.;
RT   "Sensitivity of newly established colorectal cell lines to cytotoxic
RT   drugs and monoclonal antibody drug conjugates.";
RL   Br. J. Cancer 56:722-726(1987).
//
RX   PubMed=3947514; DOI=10.1038/bjc.1986.6;
RA   Durrant L.G., Robins R.A., Pimm M.V., Perkins A.C., Armitage N.C.,
RA   Hardcastle J.D., Baldwin R.W.;
RT   "Antigenicity of newly established colorectal carcinoma cell lines.";
RL   Br. J. Cancer 53:37-45(1986).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S.,
RA   Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G.,
RA   Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J.,
RA   Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L.,
RA   Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J.,
RA   Settleman J., Seshagiri S., Zhang Z.-M.;
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M.,
RA   Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S.,
RA   Neve R.M.;
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=25926053; DOI=10.1038/ncomms8002;
RA   Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G.,
RA   Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S.,
RA   Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M.,
RA   Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.;
RT   "The molecular landscape of colorectal cancer cell lines unveils
RT   clinically actionable kinase targets.";
RL   Nat. Commun. 6:7002.1-7002.10(2015).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5;
RA   Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P.,
RA   Loewer M., Sahin U., Castle J.C.;
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//