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Cellosaurus HPDE-6/E6E7 (CVCL_S972)

[Text version]
Cell line name HPDE-6/E6E7
Synonyms HPDE6/E6E7; HPDE6-E6E7; HPDE6E6E7; Human Pancreatic Duct Epithelial-6 E6E7 immortalized
Accession CVCL_S972
Resource Identification Initiative To cite this cell line use: HPDE-6/E6E7 (RRID:CVCL_S972)
Comments Part of: ENCODE project common cell types; tier 3.
Transfected with: UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Transfected with: UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Donor information: Established from a patient suffering from a cystadenocarcinoma in the tail of her pancreas.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Cell type: Pancreatic ductal cell; CL=CL_0002079.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_0P37 (HPDE6c11)CVCL_0P38 (HPDE6c7)
Sex of cell Female
Age at sampling 63Y
Category Transformed cell line
Web pages http://genome.ucsc.edu/encode/protocols/cell/human/HPDE6-E6E7_Crawford_protocol.pdf
Publications

PubMed=8669463
Furukawa T., Duguid W.P., Rosenberg L., Viallet J., Galloway D.A., Tsao M.-S.
Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16.
Am. J. Pathol. 148:1763-1770(1996)

PubMed=11073822; DOI=10.1016/S0002-9440(10)64800-6
Ouyang H., Mou L.-J., Luk C., Liu N., Karaskova J., Squire J.A., Tsao M.-S.
Immortal human pancreatic duct epithelial cell lines with near normal genotype and phenotype.
Am. J. Pathol. 157:1623-1631(2000)

Cross-references
Biological sample resources ENCODE; ENCBS224AAA
Encyclopedic resources Wikidata; Q54890283
Experimental variables resources EFO; EFO_0005711
Gene expression databases GEO; GSM621854
GEO; GSM816639
Entry history
Entry creation03-Feb-2014
Last entry update05-Oct-2023
Version number17