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Cellosaurus LPS2 (CVCL_SA55)

Cell line name LPS2
Synonyms LP2
Accession CVCL_SA55
Resource Identification Initiative To cite this cell line use: LPS2 (RRID:CVCL_SA55)
Comments Characteristics: Derived from LPSX2, a mouse xenograft of a transplanted human liposarcoma.
Omics: Metabolome analysis.
Omics: SNP array analysis.
Disease Dedifferentiated liposarcoma (NCIt: C3704)
Dedifferentiated liposarcoma (ORDO: Orphanet_99970)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 90Y
Category Cancer cell line
Publications

PubMed=23230188; DOI=10.1158/2159-8290.CD-12-0197
Braas D., Ahler E., Tam B.M., Nathanson D., Riedinger M., Benz M.R., Smith K.B., Eilber F.C., Witte O.N., Tap W.D., Wu H., Christofk H.R.
Metabolomics strategy reveals subpopulation of liposarcomas sensitive to gemcitabine treatment.
Cancer Discov. 2:1109-1117(2012)

PubMed=23416162; DOI=10.1016/j.ajpath.2013.01.002
Smith K.B., Tran L.M., Tam B.M., Shurell E.M., Li Y.-F., Braas D., Tap W.D., Christofk H.R., Dry S.M., Eilber F.C., Wu H.
Novel dedifferentiated liposarcoma xenograft models reveal PTEN down-regulation as a malignant signature and response to PI3K pathway inhibition.
Am. J. Pathol. 182:1400-1411(2013)

PubMed=26643872; DOI=10.18632/oncotarget.6464
Kanojia D., Nagata Y., Garg M., Lee D.H., Sato A., Yoshida K., Sato Y., Sanada M., Mayakonda A., Bartenhagen C., Klein H.-U., Doan N.B., Said J.W., Mohith S., Gunasekar S., Shiraishi Y., Chiba K., Tanaka H., Miyano S., Myklebost O., Yang H., Dugas M., Meza-Zepeda L.A., Silberman A.W., Forscher C., Tyner J.W., Ogawa S., Koeffler H.P.
Genomic landscape of liposarcoma.
Oncotarget 6:42429-42444(2015)

Cross-references
Encyclopedic resources Wikidata; Q54902990
Polymorphism and mutation databases Cosmic; 2800525
Entry history
Entry creation14-May-2018
Last entry update21-Mar-2023
Version number5