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Cellosaurus LPS3 (CVCL_SA56)

Cell line name LPS3
Synonyms LP3
Accession CVCL_SA56
Resource Identification Initiative To cite this cell line use: LPS3 (RRID:CVCL_SA56)
Comments Characteristics: Derived from LPSX3, a mouse xenograft of a transplanted human liposarcoma.
Omics: Metabolome analysis.
Omics: SNP array analysis.
Disease Dedifferentiated liposarcoma (NCIt: C3704)
Dedifferentiated liposarcoma (ORDO: Orphanet_99970)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
Publications

PubMed=23230188; DOI=10.1158/2159-8290.CD-12-0197
Braas D., Ahler E., Tam B.M., Nathanson D., Riedinger M., Benz M.R., Smith K.B., Eilber F.C., Witte O.N., Tap W.D., Wu H., Christofk H.R.
Metabolomics strategy reveals subpopulation of liposarcomas sensitive to gemcitabine treatment.
Cancer Discov. 2:1109-1117(2012)

PubMed=23416162; DOI=10.1016/j.ajpath.2013.01.002
Smith K.B., Tran L.M., Tam B.M., Shurell E.M., Li Y.-F., Braas D., Tap W.D., Christofk H.R., Dry S.M., Eilber F.C., Wu H.
Novel dedifferentiated liposarcoma xenograft models reveal PTEN down-regulation as a malignant signature and response to PI3K pathway inhibition.
Am. J. Pathol. 182:1400-1411(2013)

PubMed=26643872; DOI=10.18632/oncotarget.6464
Kanojia D., Nagata Y., Garg M., Lee D.H., Sato A., Yoshida K., Sato Y., Sanada M., Mayakonda A., Bartenhagen C., Klein H.-U., Doan N.B., Said J.W., Mohith S., Gunasekar S., Shiraishi Y., Chiba K., Tanaka H., Miyano S., Myklebost O., Yang H., Dugas M., Meza-Zepeda L.A., Silberman A.W., Forscher C., Tyner J.W., Ogawa S., Koeffler H.P.
Genomic landscape of liposarcoma.
Oncotarget 6:42429-42444(2015)

Cross-references
Encyclopedic resources Wikidata; Q54902993
Polymorphism and mutation databases Cosmic; 2800526
Entry history
Entry creation14-May-2018
Last entry update21-Mar-2023
Version number5