ID   FaDu-R
AC   CVCL_SA75
DR   cancercelllines; CVCL_SA75
DR   Wikidata; Q54833222
RX   PubMed=28844650;
CC   Population: Indian.
CC   Characteristics: Established from parent cell line after a cumulative irradiation dose of 90 Gy.
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; c.151-1G>T; ClinVar=VCV000422058; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 3595; FAT1; Simple; p.Lys3277Asnfs*4 (c.9828delG) (p.Gly3276fs); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Leu (c.743G>T); ClinVar=VCV000230253; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCIt; C17262; X-Ray.
CC   Derived from site: In situ; Pharynx, hypopharynx; UBERON=UBERON_0001051.
DI   NCIt; C4043; Hypopharyngeal squamous cell carcinoma
DI   ORDO; Orphanet_494547; Squamous cell carcinoma of the hypopharynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1218 ! FaDu
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 14-05-18; Last updated: 05-10-23; Version: 12
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RX   PubMed=28844650; DOI=10.1016/j.anl.2017.07.011;
RA   Cho K.-J., Park E.-J., Kim M.-S., Joo Y.-H.;
RT   "Characterization of FaDu-R, a radioresistant head and neck cancer
RT   cell line, and cancer stem cells.";
RL   Auris Nasus Larynx 45:566-573(2017).
//