Cellosaurus cell line TCam-2 (CVCL_T012)

PubMed=8394948; DOI=10.5980/jpnjurol1989.84.1211
Mizuno Y., Gotoh A., Kamidono S., Kitazawa S.
Establishment and characterization of a new human testicular germ cell tumor cell line (TCam-2).
Nihon Hinyokika Gakkai Zasshi 84:1211-1218(1993)

PubMed=18008088; DOI=10.1007/s00441-007-0527-y
Eckert D., Nettersheim D., Heukamp L.C., Kitazawa S., Biermann K., Schorle H.
TCam-2 but not JKT-1 cells resemble seminoma in cell culture.
Cell Tissue Res. 331:529-538(2008)

PubMed=18050305; DOI=10.1002/gcc.20520
de Jong J., Stoop H., Gillis A.J.M., Hersmus R., van Gurp R.J.H.L.M., van de Geijn G.-J.M., van Drunen E., Beverloo H.B., Schneider D.T., Sherlock J.K., Baeten J., Kitazawa S., van Zoelen E.J.J., van Roozendaal K., Oosterhuis J.W., Looijenga L.H.J.
Further characterization of the first seminoma cell line TCam-2.
Genes Chromosomes Cancer 47:185-196(2008)

PubMed=20607849; DOI=10.1002/gcc.20799
Goddard N.C., McIntyre A., Gilbert D., Kitazawa S., Shipley J.M.
No evidence for V600E BRAF mutation in the seminoma cell line TCam-2.
Genes Chromosomes Cancer 49:963-966(2010)

PubMed=21668453; DOI=10.1111/j.1365-2605.2011.01170.x
Young J.C., Jaiprakash A., Mithraprabhu S., Itman C., Kitazawa R., Looijenga L.H.J., Loveland K.L.
TCam-2 seminoma cell line exhibits characteristic foetal germ cell responses to TGF-beta ligands and retinoic acid.
Int. J. Androl. 34:E204-E217(2011)

PubMed=23374840; DOI=10.1016/j.urology.2012.09.029
Russell S.M., Lechner M.G., Mokashi A.A., Megiel C., Jang J.K., Taylor C.R., Looijenga L.H.J., French C.A., Epstein A.L.
Establishment and characterization of a new human extragonadal germ cell line, SEM-1, and its comparison with TCam-2 and JKT-1.
Urology 81:464.e1-464.e9(2013)

PubMed=24812411; DOI=10.1158/1078-0432.CCR-13-2868
Feldman D.R., Iyer G., Van Alstine L., Patil S., Al-Ahmadie H., Reuter V.E., Bosl G.J., Chaganti R.S.K., Solit D.B.
Presence of somatic mutations within PIK3CA, AKT, RAS, and FGFR3 but not BRAF in cisplatin-resistant germ cell tumors.
Clin. Cancer Res. 20:3712-3720(2014)

PubMed=34153645; DOI=10.1016/j.neo.2021.05.008
Fink C., Baal N., Wilhelm J., Sarode P., Weigel R., Schumacher V., Nettersheim D., Schorle H., Schrock C., Bergmann M., Kliesch S., Kressin M., Savai R.
On the origin of germ cell neoplasia in situ: dedifferentiation of human adult Sertoli cells in cross talk with seminoma cells in vitro.
Neoplasia 23:731-742(2021)

PubMed=36899312; DOI=10.1186/s12885-023-10696-7
Schulz B., Schumacher V., Ngezahayo A., Maier-Begandt D., Schadzek N., Wilhelm J., Weidner W., Pilatz A., Fietz D., Kliesch S., Schnepel N., Hambruch N., Rode K., Langeheine M., Brehm R.
Analysis of connexin 43, connexin 45 and N-cadherin in the human Sertoli cell line FS1 and the human seminoma-like cell line TCam-2 in comparison with human testicular biopsies.
BMC Cancer 23:232.1-232.20(2023)