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Cellosaurus PC-9/S2 (CVCL_T016)

[Text version]

Cell line name PC-9/S2
Synonyms PC-9S2
Accession CVCL_T016
Resource Identification Initiative To cite this cell line use: PC-9/S2 (RRID:CVCL_T016)
Comments Omics: Deep RNAseq analysis.
Sequence variations EGFR p.Glu746_Ala750del (c.2235_2249del15) (from parent cell line).
Homozygous for TP53 p.Arg248Gln (c.743G>A) (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B260 (PC-9)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
Publications

PubMed=23733853; DOI=10.1101/gr.152322.112
Jia P., Jin H., Meador C.B., Xia J., Ohashi K., Liu L., Pirazzoli V., Dahlman K.B., Politi K., Michor F., Zhao Z., Pao W.
Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance.
Genome Res. 23:1434-1445(2013)

Cross-references
Other Wikidata; Q54938503
Polymorphism and mutation databases Cosmic; 2015226
Entry history
Entry creation03-Feb-2014
Last entry updated06-Sep-2019
Version number10