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Cellosaurus CS-1 [Human chondrosarcoma] (CVCL_T023)

[Text version]
Cell line name CS-1 [Human chondrosarcoma]
Synonyms Cs-1; CS1; CHSA cell line
Accession CVCL_T023
Resource Identification Initiative To cite this cell line use: CS-1 [Human chondrosarcoma] (RRID:CVCL_T023)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Caucasian.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Bone, humerus; UBERON=UBERON_0000976.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.36
East Asian, North1.25
East Asian, South0
South Asian0
European, North68.97
European, South29.41
Disease Chondrosarcoma (NCIt: C2946)
Chondrosarcoma (ORDO: Orphanet_55880)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81812
D7S82010,11
D13S3179
D16S53913,14
TH017,9.3
TPOX8
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=12631627
Morioka H., Weissbach L., Vogel T., Nielsen G.P., Faircloth G.T., Shao L., Hornicek F.J.
Antiangiogenesis treatment combined with chemotherapy produces chondrosarcoma necrosis.
Clin. Cancer Res. 9:1211-1217(2003)

PubMed=14637196; DOI=10.1016/j.bcp.2003.08.033
Shao L., Kasanov J., Hornicek F.J., Morii T., Fondren G., Weissbach L.
Ecteinascidin-743 drug resistance in sarcoma cells: transcriptional and cellular alterations.
Biochem. Pharmacol. 66:2381-2395(2003)

PubMed=19528443
Susa M., Morii T., Yabe H., Horiuchi K., Toyama Y., Weissbach L., Hornicek F.J., Morioka H.
Alendronate inhibits growth of high-grade chondrosarcoma cells.
Anticancer Res. 29:1879-1888(2009)

PubMed=24866169; DOI=10.1158/2326-6066.CIR-13-0224
Shen J.K., Cote G.M., Choy E., Yang P., Harmon D., Schwab J.H., Nielsen G.P., Chebib I., Ferrone S., Wang X.-H., Wang Y.-Y., Mankin H.J., Hornicek F.J., Duan Z.-F.
Programmed cell death ligand 1 expression in osteosarcoma.
Cancer Immunol. Res. 2:690-698(2014)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line databases/resources cancercelllines; CVCL_T023
Cell_Model_Passport; SIDM00199
Cosmic-CLP; 1290795
DepMap; ACH-002099
Chemistry resources GDSC; 1290795
PharmacoDB; CS1_266_2019
Encyclopedic resources Wikidata; Q54814518
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669710
Polymorphism and mutation databases Cosmic; 1992322
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation03-Feb-2014
Last entry update05-Oct-2023
Version number22