| Cell line name |
RT4v6 |
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| Synonyms |
RT4V6; RT-4-v6 |
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| Accession |
CVCL_T027 |
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| Resource Identification Initiative |
To cite this cell line use: RT4v6 (RRID:CVCL_T027) |
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| Comments |
Population: Caucasian.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255. |
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| Sequence variations |
- Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
- Gene fusion; HGNC; 3690; FGFR3 + HGNC; 11524; TACC3; Name(s)=FGFR3-TACC3 (from parent cell line).
- Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
- Mutation; HGNC; 12362; TSC1; Simple; p.Leu557Cysfs*72 (c.1669delC); ClinVar=VCV000048811; Zygosity=Homozygous (from parent cell line).
|
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| Disease |
Bladder carcinoma (NCIt: C4912) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0036 (RT-4) |
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| Sex of cell |
Male |
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| Age at sampling |
63Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=23175184; DOI=10.1038/cdd.2012.140
Jinesh G.G., Choi W., Shah J.B., Lee E.K., Willis D.L., Kamat A.M.
Blebbishields, the emergency program for cancer stem cells: sphere formation and tumorigenesis after apoptosis.
Cell Death Differ. 20:382-395(2013) PubMed=29732388; DOI=10.3233/BLC-180167
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_T027
|
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| Encyclopedic resources |
Wikidata; Q54951368
|
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| Polymorphism and mutation databases |
Cosmic; 1938696
|
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| Entry history |
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| Entry creation | 03-Feb-2014 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 14 |
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