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Cellosaurus W12 [Human keratinocyte] (CVCL_T290)

[Text version]
Cell line name W12 [Human keratinocyte]
Accession CVCL_T290
Resource Identification Initiative To cite this cell line use: W12 [Human keratinocyte] (RRID:CVCL_T290)
Comments Characteristics: Derived from a low-grade squamous intraepithelial lesion (LG-SIL).
Virology: At early passages contains about 100 HPV16 episomes per cell.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_T291 (S12 [Human keratinocyte])
Sex of cell Female
Category Transformed cell line
Publications

PubMed=2467886; DOI=10.1002/ijc.2910430422
Stanley M.A., Browne H.M., Appleby M., Minson A.C.
Properties of a non-tumorigenic human cervical keratinocyte cell line.
Int. J. Cancer 43:672-676(1989)

PubMed=16505361; DOI=10.1073/pnas.0600078103
Pett M.R., Herdman M.T., Palmer R.D., Yeo G.S.H., Shivji M.K.K., Stanley M.A., Coleman N.
Selection of cervical keratinocytes containing integrated HPV16 associates with episome loss and an endogenous antiviral response.
Proc. Natl. Acad. Sci. U.S.A. 103:3822-3827(2006)

Cross-references
Encyclopedic resources Wikidata; Q54993456
Entry history
Entry creation03-Feb-2014
Last entry update29-Jun-2023
Version number15