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Cellosaurus A0031 (CVCL_T338)

[Text version]

Cell line name A0031
Accession CVCL_T338
Resource Identification Initiative To cite this cell line use: A0031 (RRID:CVCL_T338)
Comments Population: Japanese.
Derived from sampling site: Skin.
Sequence variations Mutation; HGNC; 12791; WRN; Simple; p.Arg369Ter (c.1105C>T) (c.1336C>T); ClinVar=VCV000005449; Zygosity=Heterozygous (PubMed=25390333).
Mutation; HGNC; 12791; WRN; Simple; p.Lys1046fs*14 (c.3139-1G>C) (IVS25-1G>C); ClinVar=VCV000005447; Zygosity=Heterozygous; Note=Splice acceptor mutation (PubMed=25390333).
Disease Werner syndrome (NCIt: C3447)
Werner syndrome (ORDO: Orphanet_902)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_IN37 (A0031 iPS#23)CVCL_IN38 (A0031 iPS#34)CVCL_IN39 (A0031 iPS#64)
Originate from same individual CVCL_T339 ! B0031
Sex of cell Male
Age at sampling 37Y
Category Finite cell line
Publications

PubMed=25390333; DOI=10.1371/journal.pone.0112900
Shimamoto A., Kagawa H., Zensho K., Sera Y., Kazuki Y., Osaki M., Oshimura M., Ishigaki Y., Hamasaki K., Kodama Y., Yuasa S., Fukuda K., Hirashima K., Seimiya H., Koyama H., Shimizu T., Takemoto M., Yokote K., Goto M., Tahara H.
Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture.
PLoS ONE 9:E112900-E112900(2014)

Cross-references
Cell line collections RCB; GMC0012
Ontologies CLO; CLO_0050704
Other Wikidata; Q54606193
Entry history
Entry creation03-Feb-2014
Last entry update20-May-2021
Version number10