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Cellosaurus UPS-1 (CVCL_T762)

[Text version]
Cell line name UPS-1
Accession CVCL_T762
Resource Identification Initiative To cite this cell line use: UPS-1 (RRID:CVCL_T762)
Comments Characteristics: Defective in the uptake of fluorescent phosphatidylserine analogs by the nonendocytic pathway (PubMed=7876305).
Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Mutation; UniProtKB; A0A061HXB8; Atp11c; Simple; p.Trp836Ter (c.2508G>A) (W664X); Zygosity=Homozygous (PubMed=26420878).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=7876305; DOI=10.1083/jcb.128.5.793
Hanada K., Pagano R.E.
A Chinese hamster ovary cell mutant defective in the non-endocytic uptake of fluorescent analogs of phosphatidylserine: isolation using a cytosol acidification protocol.
J. Cell Biol. 128:793-804(1995)

PubMed=26420878; DOI=10.1194/jlr.M062547
Takada N., Takatsu H., Miyano R., Nakayama K., Shin H.-W.
ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells.
J. Lipid Res. 56:2151-2157(2015)

Cross-references
Cell line collections (Providers) RCB; RCB4451
Encyclopedic resources Wikidata; Q54991719
Entry history
Entry creation03-Feb-2014
Last entry update30-Jan-2024
Version number9