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Cellosaurus PB1 (CVCL_T881)

[Text version]
Cell line name PB1
Accession CVCL_T881
Resource Identification Initiative To cite this cell line use: PB1 (RRID:CVCL_T881)
Comments Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 8607; PRKN; Unexplicit; Ex6-7del; Zygosity=Homozygous (PubMed=23039195).
Disease Parkinson disease 2, autosomal recessive juvenile (NCIt: C198603)
Young-onset Parkinson disease (ORDO: Orphanet_2828)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_ZX89 (PB(DF))
Sex of cell Male
Age at sampling 50Y
Category Induced pluripotent stem cell
Publications

PubMed=23039195; DOI=10.1186/1756-6606-5-35
Imaizumi Y., Okada Y., Akamatsu W., Koike M., Kuzumaki N., Hayakawa H., Nihira T., Kobayashi T., Ohyama M., Sato S., Takanashi M., Funayama M., Hirayama A., Soga T., Hishiki T., Suematsu M., Yagi T., Ito D., Kosakai A., Hayashi K., Shouji M., Nakanishi A., Suzuki N., Mizuno Y., Mizushima N., Amagai M., Uchiyama Y., Mochizuki H., Hattori N., Okano H.
Mitochondrial dysfunction associated with increased oxidative stress and alpha-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.
Mol. Brain 5:35.1-35.13(2012)

Cross-references
Cell line databases/resources SKIP; SKIP000202
Encyclopedic resources Wikidata; Q54938341
Entry history
Entry creation03-Feb-2014
Last entry update29-Jun-2023
Version number11