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Cellosaurus A2780-M (CVCL_TZ68)

[Text version]
Cell line name A2780-M
Accession CVCL_TZ68
Resource Identification Initiative To cite this cell line use: A2780-M (RRID:CVCL_TZ68)
Comments Population: African American.
Characteristics: Compared to the parent cell line, has high invasiveness and motility.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=30046596

Markers:
AmelogeninX
CSF1PO10,11
D2S133821,22
D3S135814,16
D5S81811,12
D6S104311,19
D7S82010
D8S117915,17
D12S39118,19,20
D13S31712,13
D16S53911,13
D18S5116,18,19
D19S43312
D21S1128
FGA19,24
Penta D9,10
Penta E10,13
TH016
TPOX8,10
vWA15,16

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Publications

PubMed=30046596; DOI=10.1155/2018/3972534
Jiang R.-B., Cheng G.-P., Zheng Z.-G., Ni M.-W., Wan D.-Y., Feng J.-G., Gu L.-H.
Establishment and characterization of a highly metastatic ovarian cancer cell line.
BioMed Res. Int. 2018:3972534.1-3972534.9(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_TZ68
Encyclopedic resources Wikidata; Q93311561
Entry history
Entry creation13-Nov-2018
Last entry update05-Oct-2023
Version number10