| Cell line name |
PC-9/f14 |
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| Accession |
CVCL_U149 |
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| Resource Identification Initiative |
To cite this cell line use: PC-9/f14 (RRID:CVCL_U149) |
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| Comments |
Population: Japanese.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027. |
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| Sequence variations |
- Mutation; HGNC; 3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
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| Disease |
Lung adenocarcinoma (NCIt: C3512) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_B260 (PC-9) |
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| Sex of cell |
Male |
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| Age at sampling |
45Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=11506965; DOI=10.1016/S0959-8049(01)00154-X
Gemma A., Takenaka K., Hosoya Y., Matuda K., Seike M., Kurimoto F., Ono Y., Uematsu K., Takeda Y., Hibino S., Yoshimura A., Shibuya M., Kudoh S.
Altered expression of several genes in highly metastatic subpopulations of a human pulmonary adenocarcinoma cell line.
Eur. J. Cancer 37:1554-1561(2001) PubMed=17982658; DOI=10.3892/ijo.31.6.1325
Takemura A., Gemma A., Shibuya M., Matsuda K., Okano T., Nara M., Noro R., Minegishi Y., Yoshimura A., Kudoh S.
Gemcitabine resistance in a highly metastatic subpopulation of a pulmonary adenocarcinoma cell line resistant to gefitinib.
Int. J. Oncol. 31:1325-1332(2007) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_U149
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| Encyclopedic resources |
Wikidata; Q54938492
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| Polymorphism and mutation databases |
Cosmic; 915331
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| Entry history |
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| Entry creation | 03-Feb-2014 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 16 |
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