ID   PC-9/f14
AC   CVCL_U149
DR   cancercelllines; CVCL_U149
DR   Cosmic; 915331
DR   Wikidata; Q54938492
RX   PubMed=11506965;
RX   PubMed=17982658;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; 3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B260 ! PC-9
SX   Male
AG   45Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 05-10-23; Version: 16
//
RX   PubMed=11506965; DOI=10.1016/S0959-8049(01)00154-X;
RA   Gemma A., Takenaka K., Hosoya Y., Matuda K., Seike M., Kurimoto F.,
RA   Ono Y., Uematsu K., Takeda Y., Hibino S., Yoshimura A., Shibuya M.,
RA   Kudoh S.;
RT   "Altered expression of several genes in highly metastatic
RT   subpopulations of a human pulmonary adenocarcinoma cell line.";
RL   Eur. J. Cancer 37:1554-1561(2001).
//
RX   PubMed=17982658; DOI=10.3892/ijo.31.6.1325;
RA   Takemura A., Gemma A., Shibuya M., Matsuda K., Okano T., Nara M.,
RA   Noro R., Minegishi Y., Yoshimura A., Kudoh S.;
RT   "Gemcitabine resistance in a highly metastatic subpopulation of a
RT   pulmonary adenocarcinoma cell line resistant to gefitinib.";
RL   Int. J. Oncol. 31:1325-1332(2007).
//