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Cellosaurus MCAS-3 (CVCL_U210)

[Text version]
Cell line name MCAS-3
Accession CVCL_U210
Resource Identification Initiative To cite this cell line use: MCAS-3 (RRID:CVCL_U210)
Comments Population: Japanese.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 6770; SMAD4; Simple; p.Ser504Arg (c.1512T>A); Zygosity=Unspecified (from parent cell line).
Disease Ovarian mucinous cystadenocarcinoma (NCIt: C4026)
Mucinous adenocarcinoma of ovary (ORDO: Orphanet_398961)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3020 (MCAS)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=7882618; DOI=10.1007/BF00133613
Miyagi E., Yasumitsu H., Hirahara F., Nagashima Y., Minaguchi H., Miyazaki K., Umeda M.
Marked induction of gelatinases, especially type B, in host fibroblasts by human ovarian cancer cells in athymic mice.
Clin. Exp. Metastasis 13:89-96(1995)

Cross-references
Cell line databases/resources cancercelllines; CVCL_U210
Encyclopedic resources Wikidata; Q54904242
Entry history
Entry creation03-Feb-2014
Last entry update05-Oct-2023
Version number13