ID   MCAS-3
AC   CVCL_U210
DR   cancercelllines; CVCL_U210
DR   Wikidata; Q54904242
RX   PubMed=7882618;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6770; SMAD4; Simple; p.Ser504Arg (c.1512T>A); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
DI   NCIt; C4026; Ovarian mucinous cystadenocarcinoma
DI   ORDO; Orphanet_398961; Mucinous adenocarcinoma of ovary
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3020 ! MCAS
SX   Female
AG   60Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 05-10-23; Version: 13
//
RX   PubMed=7882618; DOI=10.1007/BF00133613;
RA   Miyagi E., Yasumitsu H., Hirahara F., Nagashima Y., Minaguchi H.,
RA   Miyazaki K., Umeda M.;
RT   "Marked induction of gelatinases, especially type B, in host
RT   fibroblasts by human ovarian cancer cells in athymic mice.";
RL   Clin. Exp. Metastasis 13:89-96(1995).
//