ID   HT4
AC   CVCL_U378
SY   HT-4
DR   Wikidata; Q54896597
RX   PubMed=1980069;
RX   PubMed=2033646;
CC   Characteristics: At the restrictive temperature (39 Celsius) the cells take on properties of differentiated neurons they express neuronal antigens, synthesize NGF mRNA, and secrete biologically active NGF in vitro.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [tsA58].
OX   NCBI_TaxID=10090; ! Mus musculus
CA   Transformed cell line
DT   Created: 03-02-14; Last updated: 07-09-18; Version: 7
RX   PubMed=1980069; DOI=10.1016/0896-6273(90)90347-I;
RA   Morimoto B.H., Koshland D.E. Jr.;
RT   "Induction and expression of long- and short-term neurosecretory
RT   potentiation in a neural cell line.";
RL   Neuron 5:875-880(1990).
RX   PubMed=2033646; DOI=10.1002/jnr.490280203;
RA   Whittemore S.R., Holets V.R., Keane R.W., Levy D.J., McKay R.D.G.;
RT   "Transplantation of a temperature-sensitive, nerve growth
RT   factor-secreting, neuroblastoma cell line into adult rats with
RT   fimbria-fornix lesions rescues cholinergic septal neurons.";
RL   J. Neurosci. Res. 28:156-170(1991).