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Cellosaurus CHO 25-RA (CVCL_U429)

[Text version]

Cell line name CHO 25-RA
Synonyms 25-RA; 25RA; Clone 25-RA; 25 RA CHO
Accession CVCL_U429
Resource Identification Initiative To cite this cell line use: CHO 25-RA (RRID:CVCL_U429)
Comments Derived from sampling site: Ovary.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
CVCL_U430 (CHO AC29)CVCL_U431 (CHO CT43)CVCL_U432 (CHO CT52)
CVCL_U433 (CHO CT60)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

Chang T.Y., Limanek J.S.
Regulation of cytosolic acetoacetyl coenzyme A thiolase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and mevalonate kinase by low density lipoprotein and by 25-hydroxycholesterol in Chinese hamster ovary cells.
J. Biol. Chem. 255:7787-7795(1980)

Cadigan K.M., Heider J.G., Chang T.-Y.
Isolation and characterization of Chinese hamster ovary cell mutants deficient in acyl-coenzyme A:cholesterol acyltransferase activity.
J. Biol. Chem. 263:274-282(1988)

PubMed=2404988; DOI=10.1083/jcb.110.2.295
Cadigan K.M., Spillane D.M., Chang T.Y.
Isolation and characterization of Chinese hamster ovary cell mutants defective in intracellular low density lipoprotein-cholesterol trafficking.
J. Cell Biol. 110:295-308(1990)

PubMed=8898195; DOI=10.1016/S0092-8674(00)81362-8
Hua X., Nohturfft A., Goldstein J.L., Brown M.S.
Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein.
Cell 87:415-426(1996)

Other Wikidata; Q54812550
Entry history
Entry creation03-Feb-2014
Last entry update12-Mar-2020
Version number6