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Cellosaurus U-937 GTB (CVCL_U631)

[Text version]

Cell line name U-937 GTB
Synonyms U-937-GTB; U-937/GTB; U937/GTB; U937-GTB
Accession CVCL_U631
Resource Identification Initiative To cite this cell line use: U-937 GTB (RRID:CVCL_U631)
Comments Derived from sampling site: Pleural effusion.
Sequence variations PICALM-MLLT10 (CALM-AF10) gene fusion (from parent cell line).
Hemizygous for PTEN p.Gly129fs*51 (c.387_388insCGCC) (from parent cell line).
Homozygous for TP53 c.559+1G>A (p.Val173Trpfs*59); splice donor mutation (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0007 (U-937)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
Chemistry resources ChEMBL-Cells; CHEMBL3308007
ChEMBL-Targets; CHEMBL612795
Other Wikidata; Q54973607
Entry history
Entry creation16-Apr-2014
Last entry update02-Jul-2020
Version number8