Cellosaurus logo
expasy logo

Cellosaurus XP7BE (CVCL_U669)

[Text version]
Cell line name XP7BE
Synonyms XP7 BE; Xeroderma Pigmentosum 7 BEthesda; Te Ko; TeKo; GM02590
Accession CVCL_U669
Resource Identification Initiative To cite this cell line use: XP7BE (RRID:CVCL_U669)
Comments Population: Caucasian.
Senescence: Senesces at 26 PDL (PubMed=6492896).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Xeroderma pigmentosum, complementation group D (NCIt: C3967)
Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7359 ! XP7BE LCL
Sex of cell Female
Age at sampling 14Y
Category Finite cell line
Publications

PubMed=4811796; DOI=10.7326/0003-4819-80-2-221
Robbins J.H., Kraemer K.H., Lutzner M.A., Festoff B.W., Coon H.G.
Xeroderma pigmentosum. An inherited disease with sun sensitivity, multiple cutaneous neoplasms, and abnormal DNA repair.
Ann. Intern. Med. 80:221-248(1974)

PubMed=273925; DOI=10.1073/pnas.75.4.1984
Andrews A.D., Barrett S.F., Robbins J.H.
Xeroderma pigmentosum neurological abnormalities correlate with colony-forming ability after ultraviolet radiation.
Proc. Natl. Acad. Sci. U.S.A. 75:1984-1988(1978)

PubMed=643622; DOI=10.1093/nar/5.3.951
Kuhnlein U., Lee B., Penhoet E.E., Linn S.M.
Xeroderma pigmentosum fibroblasts of the D group lack an apurinic DNA endonuclease species with a low apparent Km.
Nucleic Acids Res. 5:951-960(1978)

PubMed=7273335; DOI=10.1093/carcin/2.6.567
Simon L., Hazard R.M., Maher V.M., McCormick J.J.
Enhanced cell killing and mutagenesis by ethylnitrosourea in xeroderma pigmentosum cells.
Carcinogenesis 2:567-570(1981)

PubMed=6492896; DOI=10.1016/0047-6374(84)90044-7
Cleaver J.E.
DNA repair deficiencies and cellular senescence are unrelated in xeroderma pigmentosum cell lines.
Mech. Ageing Dev. 27:189-196(1984)

PubMed=1372108; DOI=10.1016/0921-8777(92)90072-b
Johnson R.T., Squires S.
The XPD complementation group. Insights into xeroderma pigmentosum, Cockayne's syndrome and trichothiodystrophy.
Mutat. Res. 273:97-118(1992)

Cross-references
Cell line collections (Providers) ATCC; CRL-1200 - Discontinued
Coriell; GM02590 - Discontinued
JCRB; KURB1072
Encyclopedic resources Wikidata; Q54972006
Entry history
Entry creation16-Apr-2014
Last entry update29-Jun-2023
Version number11