ID   AILNCaP
AC   CVCL_U984
SY   AI LNCaP; AI-LNCaP; Androgen-Independent LNCaP
DR   BTO; BTO:0004799
DR   cancercelllines; CVCL_U984
DR   Wikidata; Q54748998
RX   PubMed=16931574;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1379 ! LNCaP clone FGC
SX   Male
AG   50Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 05-10-23; Version: 16
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RX   PubMed=16931574; DOI=10.1210/me.2006-0033;
RA   Inoue T., Yoshida T., Shimizu Y., Kobayashi T., Yamasaki T., Toda Y.,
RA   Segawa T., Kamoto T., Nakamura E., Ogawa O.;
RT   "Requirement of androgen-dependent activation of protein kinase Czeta
RT   for androgen-dependent cell proliferation in LNCaP Cells and its roles
RT   in transition to androgen-independent cells.";
RL   Mol. Endocrinol. 20:3053-3069(2006).
//